Sino Biological, Inc. (Shenzhen Stock Exchange: 301047.SZ) announced the launch of its XPressMAX™ Cell-Free Protein Synthesis Kit (Cat#: CFKIT02), designed to enhance artificial intelligence (AI)-powered high-throughput screening for antibody drug discovery. The kit uses advanced cell-free protein synthesis technology to produce target proteins and antibodies rapidly in vitro, bypassing the limitations of traditional cell-based expression systems.
The XPressMAX™ kit is based on an E. coli lysate fully supplemented with transcription and translation components, enabling direct synthesis from plasmid or PCR templates. It supports expression of VHH, scFv, Fab, and miniproteins, which are critical for antibody discovery. The company has established a high-throughput cell-free expression platform that validates over 2,000 scFv/VHH molecules in 3-4 weeks, matching the rapid iteration of AI.
Key highlights of the kit include ultra-fast synthesis completed in just 3 hours, a success rate greater than 99%, and support for complex disulfide bonding without additional enhancers, ensuring native folding and bioactivity. According to Dr. Rob Burgess, Chief Business Officer at Sino Biological US, Inc., the kit represents a significant advancement in research tools for next-generation therapeutic discovery, helping partners compress antibody discovery timelines without compromising quality. Dr. Jie Zhang, Sino Biological’s General Manager, noted that AI is revolutionizing antibody screening but demands expression systems that match its speed, and XPressMAX™ achieves rapid, high-success expression of challenging proteins in as little as 3 hours.
The launch addresses the growing need for faster protein expression to keep pace with AI-driven discovery. By integrating with AI screening platforms, researchers can dramatically accelerate identification and optimization of antibody candidates, reducing development costs and timelines. The kit is available for researchers to explore at www.sinobiological.com/other-products/cell-free-protein-synthesis-system-cfkit02 or request a free sample via this form.
Sino Biological is an international reagent supplier and CRO service provider specializing in recombinant protein production and antibody development, with facilities in Houston and Canada serving researchers in over 90 countries.
