Creative Diagnostics, a leading manufacturer and supplier of antibodies, antigens and assay kits, has announced its Hantavirus Research Reagents and Products to support hantavirus research and diagnostic assay development. This comprehensive catalog can help academic researchers, biopharmaceutical companies, and industrial organizations accelerate the development of diagnostic assays and therapeutic interventions targeting dangerous rodent-borne orthohantaviruses.
Hantaviruses are emerging zoonotic pathogens classified as Category A pathogens by the U.S. Centers for Disease Control and Prevention (CDC). They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), both of which have high fatality rates. The viruses are transmitted to humans through aerosols from infected rodent excreta. The hantavirus genome consists of three RNA segments (S, M, L) that encode the nucleocapsid protein (N), glycoproteins Gn and Gc, and RNA-dependent RNA polymerase (RdRp). The N protein protects viral RNA and plays a role in transcription and replication.
Currently, no antiviral therapies or vaccines are approved for hantavirus diseases. Understanding the molecular mechanisms of the virus life cycle could identify targets for antiviral therapy. Given the high case-fatality rates, developing effective vaccines is imperative. Additionally, early clinical symptoms resemble seasonal respiratory illnesses, so sensitive and reliable laboratory diagnostics are urgently needed for early differential diagnosis.
To address these challenges, Creative Diagnostics offers a range of hantavirus research reagents covering multiple strains, including Hantavirus, Puumala virus (PUUV), Seoul virus (SEOV), and Sin Nombre virus (SNV). The product line includes: 1) Recombinant hantavirus antigens for assay development; 2) high-affinity monoclonal and polyclonal antibodies validated for capture and detection across platforms such as Western blot, flow cytometry, immunohistochemistry, and surface plasmon resonance; 3) supporting reagents for ELISA and rapid immunoassay research.
For detailed product specifications, volume pricing, or to browse the complete list of available viral solutions, visit the official product portal at https://www.creative-diagnostics.com/hantavirus.htm.
