Aclarion, Inc. (Nasdaq: ACON, ACONW), a commercial-stage healthcare technology company, announced the issuance of U.S. Patent #12,601,803, titled “System for Machine Learning-Based Model Training and Prediction for Evaluation of Pain.” The patent covers the company’s machine learning-based platform for analyzing magnetic resonance spectroscopy (MRS) data to help physicians identify the location of chronic low back pain.
The patent strengthens Aclarion’s ability to scale by protecting its use of AI in future versions of the Nociscan platform. Nociscan is a cloud-based platform that converts complex MRS spectral data into clinically actionable insights, helping physicians distinguish between painful and non-painful discs in the spine. The newly issued patent covers machine learning models that extract quantitative biomarkers from MRS spectral data to generate standardized classifications associated with pain-related conditions. It also covers AI-based automated data quality controls that detect and exclude low-quality acquisition signals, such as excessive lipids, low signal-to-noise ratio, or spectral artifacts.
“This patent strengthens the foundation of our platform by protecting how we leverage AI to transform complex spectroscopy data into meaningful, actionable information that physicians can integrate into everyday practice,” said Brent Ness, Chief Executive Officer of Aclarion. “By combining proprietary signal processing with machine learning, we are building a scalable and defensible approach to evaluating pain that has the potential to redefine how spine conditions are assessed while enabling highly efficient scaling and strong gross margin expansion.”
The patent expands Aclarion’s intellectual property portfolio to 64 issued and pending patents worldwide, underscoring its strategy to build a differentiated, software-driven platform in the large and underserved chronic low back pain market. Chronic low back pain affects approximately 266 million people globally. When used alongside other diagnostic tools, clinical data has demonstrated up to a 97% surgical success rate when all Nociscan-positive discs are treated.
To read the patent, click here. For more news from Aclarion, visit their Latest News page. To find a Nociscan center, view the site map here.


